●Highly efficient transfection Highly efficient RNA (siRNA, miRNA, mRNA, shRNA) transfection in a wide variety of cells including primary cells and suspension cells.
●Low Cellular Toxicity Transfection with serum, no need to add additional medium or replace the medium after transfection because of low cellular toxicity.
●High Knockdown Efficiency Many SCI papers proved. Here is part of the papers citing use of Engreen RNA transfection reagents.
Biochim Biophys Acta Mol Basis Dis. 2019 Dec 1;1865(12):165540. doi: 10.1016/j.bbadis.2019.165540. Epub 2019 Aug 27.
G-MDSC-derived exosomes attenuate collagen-induced arthritis by impairing Th1 and Th17 cell responses.
Mol Ther Nucleic Acids. 2019 Sep 6;17:38-48. doi: 10.1016/j.omtn.2019.05.004. Epub 2019 May 22.
Circular RNA Expression Profiling and the Potential Role of hsa_circ_0089172 in Hashimoto’s Thyroiditis via Sponging miR125a-3p.
Biosci Rep. 2019 Aug 19;39(8). pii: BSR20190109. doi: 10.1042/BSR20190109. Print 2019 Aug 30.
Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway.
J Autoimmun. 2019 Aug;102:96-113. doi: 10.1016/j.jaut.2019.04.018. Epub 2019 May 23.
NF-κB-driven miR-34a impairs Treg/Th17 balance via targeting Foxp3.
Cancer Lett. 2019 May 28;450:110-122. doi: 10.1016/j.canlet.2019.02.029. Epub 2019 Feb 18.
STAT3 inhibition enhances CDN-induced STING signaling and antitumor immunity.
Chemosphere. 2019 May;223:165-170. doi: 10.1016/j.chemosphere.2019.01.169. Epub 2019 Feb 1.
Polychlorinated diphenyl sulfides can induce ROS and genotoxicity via the AhR-CYP1A1 pathway.
Leuk Lymphoma. 2019 Mar;60(3):772-781. doi: 10.1080/10428194.2018.1493727. Epub 2019 Jan 15.
Targeting the cross-talk between the hedgehog and NF-κB signaling pathways in multiple myeloma.
Mol Cancer. 2019 Mar 30;18(1):61. doi: 10.1186/s12943-019-0978-2.
Long noncoding RNA Pvt1 regulates the immunosuppression activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice.
Int J Mol Med. 2018 Jun;41(6):3379-3393. doi: 10.3892/ijmm.2018.3526. Epub 2018 Mar 1.
MicroRNA-155 inhibits the osteogenic differentiation of mesenchymal stem cells induced by BMP9 via downregulation of BMP signaling pathway.
J Virol. 2018 Apr 13;92(9). pii: e00033-18. doi: 10.1128/JVI.00033-18. Print 2018 May 1.
Lactic acid downregulates viral microRNA to promote Epstein-Barr Virus-immortalized B lymphoblastic cell adhesion and growth.
Mol Med Rep. 2018 Apr;17(4):5851-5859. doi: 10.3892/mmr.2018.8601. Epub 2018 Feb 13.
Long non‑coding RNA BC168687 small interfering RNA reduces high glucose and high free fatty acid‑induced expression of P2X7 receptors in satellite glial cells.
Biofactors. 2018 Mar;44(2):123-136. doi: 10.1002/biof.1395. Epub 2017 Nov 29.
Dihydromyricetin inhibits NLRP3 inflammasome-dependent pyroptosis by activating the Nrf2 signaling pathway in vascular endothelial cells.
Exp Cell Res. 2017 Dec 15;361(2):342-352. doi: 10.1016/j.yexcr.2017.11.002. Epub 2017 Nov 2.
Erythropoietin ameliorates early brain injury after subarachnoid haemorrhage by modulating microglia polarization via the EPOR/JAK2-STAT3 pathway.
J Cell Mol Med. 2017 Apr;21(4):802-815. doi: 10.1111/jcmm.13022. Epub 2016 Nov 25.
A novel P53/POMC/Gαs/SASH1 autoregulatory feedback loop activates mutated SASH1 to cause pathologic hyperpigmentation.
J Exp Clin Cancer Res. 2016 Sep 17;35(1):145. doi: 10.1186/s13046-016-0423-y.
Demystifying the mechanistic and functional aspects of p21 gene activation with double-stranded RNAs in human cancer cells.
J Orthop Translat. 2016 Jun 8;7:1-6. doi: 10.1016/j.jot.2016.05.011. eCollection 2016 Oct.
Knockdown of asporin affects transforming growth factor-β1-induced matrix synthesis in human intervertebral annulus cells.
Immunol Res. 2016 Apr;64(2):489-96. doi: 10.1007/s12026-015-8715-4.
Upregulation of long noncoding RNA TMEVPG1 enhances T helper type 1 cell response in patients with Sjögren syndrome.
Stem Cells Dev. 2016 Mar 15;25(6):477-91. doi: 10.1089/scd.2015.0301. Epub 2016 Feb 22.
High-Efficient Transfection of Human Embryonic Stem Cells by Single-Cell Plating and Starvation.
Mol Med Rep. 2016 Mar;13(3):2492-8. doi: 10.3892/mmr.2016.4814. Epub 2016 Jan 27.
Downregulated microRNA-23b promotes BMP9-mediated osteogenesis in C2C12 myoblast cells by targeting Runx2.
Int J Mol Med. 2015 Dec;36(6):1497-506. doi: 10.3892/ijmm.2015.2363. Epub 2015 Oct 9.
miR-21 synergizes with BMP9 in osteogenic differentiation by activating the BMP9/Smad signaling pathway in murine multilineage cells.
Mol Biosyst. 2015 Nov;11(11):3040-7. doi: 10.1039/c5mb00347d.
The involvement of aquaporin 1 in the hepatopulmonary syndrome rat serum-induced migration of pulmonary arterial smooth muscle cells via the p38-MAPK pathway.
Tumour Biol. 2016 Mar;37(3):3479-88. doi: 10.1007/s13277-015-4086-7. Epub 2015 Oct 9.
MiR-30a regulates the proliferation, migration, and invasion of human osteosarcoma by targeting Runx2.
Endocrine. 2015 Aug;49(3):752-60. doi: 10.1007/s12020-015-0546-5. Epub 2015 Feb 11.
MiR-346 regulates CD4⁺CXCR5⁺ T cells in the pathogenesis of Graves’ disease.
J Immunol. 2015 Aug 1;195(3):1301-11. doi: 10.4049/jimmunol.1500209. Epub 2015 Jun 19.
MicroRNA-9 Regulates the Differentiation and Function of Myeloid-Derived Suppressor Cells via Targeting Runx1.
Immunol Res. 2015 Jun;62(2):129-36. doi: 10.1007/s12026-015-8643-3.
Decreased expression of microRNA-125a-3p upregulates interleukin-23 receptor in patients with Hashimoto’s thyroiditis.
PLoS One. 2015 Mar 31;10(3):e0121510. doi: 10.1371/journal.pone.0121510. eCollection 2015.
MicroRNA-22 impairs anti-tumor ability of dendritic cells by targeting p38.
Apoptosis. 2015 Jan;20(1):92-109. doi: 10.1007/s10495-014-1058-0.
RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells.
Mol Biosyst. 2014 Apr;10(4):759-66. doi: 10.1039/c3mb70391f. Epub 2014 Jan 23.
Paxillin suppresses the proliferation of HPS rat serum treated PASMCs by up-regulating the expression of cytoskeletal proteins.
Apoptosis. 2013 Nov;18(11):1348-1362. doi: 10.1007/s10495-013-0866-y.
The histone deacetylase inhibitor vorinostat prevents TNFα-induced necroptosis by regulating multiple signaling pathways.
Cell Signal. 2013 Jun;25(6):1526-38. doi: 10.1016/j.cellsig.2012.12.025. Epub 2013 Jan 16.
SASH1 regulates melanocyte transepithelial migration through a novel Gαs-SASH1-IQGAP1-E-Cadherin dependent pathway.
J Immunol. 2013 Mar 1;190(5):2437-46. doi: 10.4049/jimmunol.1202282. Epub 2013 Jan 25.
Multiple tumor-associated microRNAs modulate the survival and longevity of dendritic cells by targeting YWHAZ and Bcl2 signaling pathways.
Respir Physiol Neurobiol. 2013 Jan 15;185(2):332-8. doi: 10.1016/j.resp.2012.09.009. Epub 2012 Oct 8.
Effect of annexin A2 on hepatopulmonary syndrome rat serum-induced proliferation of pulmonary arterial smooth muscle cells.
Genes Immun. 2012 Dec;13(8):621-31. doi: 10.1038/gene.2012.45. Epub 2012 Oct 4.
TGF-β-associated miR-27a inhibits dendritic cell-mediated differentiation of Th1 and Th17 cells by TAB3, p38 MAPK, MAP2K4 and MAP2K7.
Cytokine. 2012 Nov;60(2):505-13. doi: 10.1016/j.cyto.2012.06.317. Epub 2012 Jul 31.
BLyS expression and JNK activation may form a feedback loop to promote survival and proliferation of multiple myeloma cells.
Biochem J. 2012 Nov 1;447(3):407-16. doi: 10.1042/BJ20120256.
Promoter-associated small double-stranded RNA interacts with heterogeneous nuclear ribonucleoprotein A2/B1 to induce transcriptional activation.
J Cell Sci. 2012 Sep 15;125(Pt 18):4219-29. doi: 10.1242/jcs.086553. Epub 2012 May 28.
Regulation of apoptosis by Bat3-enhanced YWK-II/APLP2 protein stability.
J Radiat Res. 2012 Jul;53(4):516-25. doi: 10.1093/jrr/rrs002. Epub 2012 Jun 6.
MicroRNA-148b enhances the radiosensitivity of non-Hodgkin’s Lymphoma cells by promoting radiation-induced apoptosis.
Genes Immun. 2012 Jun;13(4):311-20. doi: 10.1038/gene.2011.87. Epub 2012 Jan 26.
Global mapping of H3K4me3 and H3K27me3 reveals chromatin state-based regulation of human monocyte-derived dendritic cells in different environments.
Cell Biochem Funct. 2012 Mar;30(2):108-13. doi: 10.1002/cbf.1823. Epub 2011 Oct 26.
The effects of myocyte enhancer factor 2A gene on the proliferation, migration and phenotype of vascular smooth muscle cells.
Virus Res. 2012 Jan;163(1):183-9. doi: 10.1016/j.virusres.2011.09.016. Epub 2011 Sep 16.
Small interfering RNA against the 2C genomic region of coxsackievirus B3 exerts potential antiviral effects in permissive HeLa cells.
J Sex Med. 2011 Oct;8(10):2773-80. doi: 10.1111/j.1743-6109.2011.02412.x. Epub 2011 Aug 5.
Up-regulation of VEGF by small activator RNA in human corpus cavernosum smooth muscle cells.
J Immunol. 2011 Apr 15;186(8):4716-24. doi: 10.4049/jimmunol.1002989. Epub 2011 Mar 7.
Both miR-17-5p and miR-20a alleviate suppressive potential of myeloid-derived suppressor cells by modulating STAT3 expression.
Microvasc Res. 2010 Jul;80(1):158-65. doi: 10.1016/j.mvr.2010.01.003. Epub 2010 Jan 14.
A PKC-beta inhibitor treatment reverses cardiac microvascular barrier dysfunction in diabetic rats.
Apoptosis. 2010 Apr;15(4):488-98. doi: 10.1007/s10495-009-0439-2.
A PKC-beta inhibitor protects against cardiac microvascular ischemia reperfusion injury in diabetic rats.
J Biol Chem. 2010 Apr 2;285(14):10890-901. doi: 10.1074/jbc.M109.058347. Epub 2010 Jan 26.
Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction.
Contents & storage
Material safety data sheets (MSDS)
For Research Use Only. Not for use in diagnostic procedures.
